Year: 2013 | Month: November | Volume 6 | Issue 4s
Effect of Ethanol on Membrane Stability in Oreochromis Mossambicus (Peters)
Abstract: <div>Excess production and usage of ethanol as an alternative fuel has resulted in frequent ethanol spillage, which brings about massive fish kills arising due to depletion in oxygen content by ethanol, and data available so far on the impact of ethanol on aquatic ecosystems are scarce. The present investigates the alterations in the membrane stability after in vitro and in vivo exposure of fish erythrocytes and lysosomes to ethanol at different sub lethal concentrations. Oreochromis mossambicus (Peters) was selected as an animal model and the LC50 value of ethanol was found to be 13.01 g/l. Ethanol brings about considerable damage to the RBCs when subjected to in vitro and in vivo conditions of different ethanol concentrations and it was</div><div>found to be highly significant at 0.1% level. Similarly a significant decrease (P<0.001) in lysosomal fraction of â-glucuronidase and acid phosphatase activities were observed both in in vitro and in vivo studies. Ethanol induced mutilations to the membrane of RBCs and lysosomes when subjected to different concentrations of ethanol both in in-vivo and in vitro conditions are found to be very momentous.</div>
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